Tag: Well-Being

Exercise and Cancer Cells: High-Intensity Exercise = High-Intensity Results [RESEARCH]

(Title image: Photo by Blocks Fletcher on Unsplash)

I am a huge proponent of exercise, both for prevention of cancer and its recurrence and in management of cancer treatment side effects, not to mention improving quality-of-life. Now a new study shows how even just one exercise session can have a powerful effect on cancer cells.

A randomized controlled trial conducted by researchers in Australia (Bettariga et al., 2025, Breast Cancer Res Treat) explored the effects of a single bout of vigorous activity (either weightlifting or interval training) on the production of anti-cancer myokines and investigated how blood drawn from study participants affected live cancer cells in the laboratory.

There has been a lot of research on the efficacy of exercise in reducing the risk of both developing cancer and preventing recurrence. However, this study focused exclusively on breast cancer survivors, which was important given that the physiology of survivors is affected by the treatments that they’ve gone through.

What was so gratifying to me was to see the significant effect of strenuous exercise. While the greatest benefit was seen from high-intensity interval training regarding its lethal effect on live breast cancer cells due to particularly high levels of a myokine called IL-6, the researchers stressed that strength training was likewise important as a cancer-fighting activity because building muscle through exercise also increased the amount of myokines circulating through the body.

The study participants engaged in strenuous exercise, but the program was created with noice exercisers in mind.
(Photo by Intenza Fitness on Unsplash)

It’s important to note that all thirty-two participants in this study were not exercising prior to joining the research group. Even so, they were able to tolerate the high intensity of the workouts. Keep in mind that “high intensity” is relative to the individual. That means strenuous exercise (for this study, reaching an effort level of at least a 7 or 8 on a scale of 1 to 10) will be different for a novice exerciser versus a highly-trained professional athlete.

So often, I encounter people who are willing to take a plethora of medications with considerable side effects, but roll their eyes when exercise is mentioned. Some people view physical activity as being only for those who are interested in looking a certain way or being mainly for those who have already reached a certain level of fitness.

Nothing could be further from the truth. Exercise is for everyone. We all start at different points; where exactly that is doesn’t matter. What does matter is that we are willing to exert enough energy to make a difference in our physiology and our well-being.

This is not “diet culture” or anything to do with body shaming. This is about doing what you can personally to increase your chances of a cancer-free life.

Survivors can talk to their healthcare team, show them this research and request that doctors lobby their insurance companies. Personal training, subsidized exercise equipment and gym memberships, fitness classes at cancer centers—all of these should be considered a critical part of cancer treatment and survivorship.

REFERENCES

Reader-Friendly Article:
Reynolds G (September 11, 2025) “A single exercise session may slow cancer cell growth, new study shows.” Washington Post. Free access via MSN: https://www.msn.com/en-us/health/other/a-single-exercise-session-may-slow-cancer-cell-growth-new-study-shows/ar-AA1Ml2oc?ocid=socialshare

Research Study:
Full publication
Bettariga F, Taaffe DR, Crespo-Garcia C, Clay TD, De Santi M, Baldelli G, Adhikari S, Gray ES, Galvão DA, Newton RU (2025) A single bout of resistance or high-intensity interval training increases anti-cancer myokines and suppresses cancer cell growth in vitro in survivors of breast cancer. Breast Cancer Res Treat, 213, 171-180. https://link.springer.com/article/10.1007/s10549-025-07772-w
PubMed Listing
https://pubmed.ncbi.nlm.nih.gov/40608178/

Paying a Compliment, the Happiest Transaction

~There are precious things that cost nothing.~

I’m currently taking a class via Coursera.org by Prof. Laurie Santos of Yale entitled, “The Science of Well-Being“, which I expect to cover in more depth in a future post.

The purpose of the class is to present research on happiness, why we don’t have it (the things we think will make us happy, don’t) and how we can get it (what actually makes us happy may be surprising).

Of the many studies that Dr. Santos discusses, one in particular caught my interest. University of Chicago researcher Nicholas Epley investigated the impact that social connections have on our happiness (“Mistakenly seeking solitude“). Briefly, he found that individuals who made even superficial contact with someone else during their commute to work on a train not only felt happier, but the person with whom they struck up a conversation likewise felt happier that day.

Making an effort to bridge the gap between us benefits everyone.

But this can be uncomfortable to do. Quite often, people taking public transport keep to themselves. Even if we know that striking up a conversation might be pleasant – and even increase our happiness – we may feel too self-conscious to engage with a stranger.

This made me think: some of the most rewarding interactions that I’ve had with strangers have consisted of merely eliciting a smile from them. That is a very brief connection with another human that ends up bringing both of us joy.

And the best way to do that? Pay them a compliment. I have been gifted with the most beautiful and sincere smiles from others by complimenting them on something about them that was genuinely laudable, resulting in good feelings that last an unexpectedly long time. Try it and see!

This world needs more diverse people finding common connections with each other.

Furthermore, when you open yourself to finding something to compliment about another person, it is amazing how quickly you can locate it. Your eyes see things more brightly and happily, and that feeling is passed on to your recipient along with your kind words.

Then, if their smiles last long enough for their good mood to positively benefit someone else, perhaps that simple act of a compliment can send a ripple that becomes something so much bigger.

What a lovely gift to the world.